Term Name: | Mre11 complex |
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Synonyms: | MRN complex, MRX complex, Rad50 complex, RAD50-MRE11-NBN complex, Rad50-Rad32-Nbs1 complex, RMX complex |
Definition: | Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins. |
Ontology: | GO: Cellular Component [GO:0030870] QuickGO AmiGO |