Term Name: | ammonia assimilation cycle |
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Synonyms: | glutamate metabolic process via glutamine and ammonia, glutamate metabolism via glutamine and ammonia |
Definition: | The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen. |
Ontology: | GO: Biological Process [GO:0019676] QuickGO AmiGO |