Term Name: | oxidative phosphorylation uncoupler activity |
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Synonyms: | mitochondrial uncoupling protein activity, uncoupling protein activity |
Definition: | Enables the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis. |
Ontology: | GO: Molecular Function [GO:0017077] QuickGO AmiGO |