Term Name: NuRD complex
Synonyms: Mi-2 complex, NRD complex, nucleosome remodeling and histone deacetylation complex
Definition: An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.
Ontology: GO: Cellular Component [GO:0016581]    QuickGO    AmiGO

Relationships
is a type of: CHD-type complex histone deacetylase complex transcription regulator complex
has subtype: SHREC complex