Term Name: | RISC complex |
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Synonyms: | micro-ribonucleoprotein complex, miRNP complex, RNA-induced silencing complex |
Definition: | A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation. |
Ontology: | GO: Cellular Component [GO:0016442] QuickGO AmiGO |