Term Name: | 7-methylguanosine RNA capping |
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Synonyms: | m(7)G RNA capping, RNA capping |
Definition: | The sequence of enzymatic reactions by which the RNA 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript. Additional methylation can occur on the ribose sugars of the first and second nucleotides adjacent to the m7G nRNA cap. These methylations are often referred to as N6,2'-O-dimethyladenosine (m6,2A) and N6,2'-O-dimethylguanosine (m6,2G), respectively. |
Ontology: | GO: Biological Process [GO:0009452] QuickGO AmiGO |