Term Name: | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity |
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Synonyms: | 7,8-dihydro-8-oxoguanine-triphosphatase activity, 8-oxo-7,8-dihydroguanine triphosphatase activity, 8-oxo-7,8-dihydroguanosine triphosphatase activity, 8-oxo-GTPase activity |
Definition: | Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) + H2O = 8-oxo-7,8-dihydroguanosine diphosphate (8-oxo-GDP) + phosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription. |
Ontology: | GO: Molecular Function [GO:0008413] QuickGO AmiGO |