Term Name: | COP9 signalosome |
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Synonyms: | COP9 complex, CSN, signalosome |
Definition: | A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome. |
Ontology: | GO: Cellular Component [GO:0008180] QuickGO AmiGO |