Term Name: | metaphase/anaphase transition of mitotic cell cycle |
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Synonyms: | metaphase/anaphase transition by anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process, mitotic metaphase/anaphase transition |
Definition: | The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin. |
Ontology: | GO: Biological Process [GO:0007091] QuickGO AmiGO |