Term Name:	pyruvate decarboxylation to acetyl-CoA
Synonyms:	acetyl-CoA anabolism from pyruvate, acetyl-CoA biosynthetic process from pyruvate, acetyl-CoA formation from pyruvate, acetyl-CoA synthesis from pyruvate, oxidative decarboxylation of pyruvate, pyruvate decarboxylation, pyruvate dehydrogenase pathway
Definition:	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate. In most organisms, this pathway links glycolysis to the TCA cycle, by a series of three reactions carried out by a multisubunit complex called the 'pyruvate dehydrogenase complex', even though pyruvate dehydrogenase activity describes only one of those reactions. The combination of the three reactions can be summarized as: pyruvate + coenzyme A + NAD+ -> acetyl-CoA + CO2 + NADH.
Ontology:	GO: Biological Process [GO:0006086]    QuickGO    AmiGO