Term Name: | phosphatidylinositol 3-kinase complex, class IB |
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Synonyms: | 1-phosphatidylinositol-4-phosphate 3-kinase, class IB complex, 1-phosphatidylinositol-4-phosphate kinase, class IB complex, class IB PI3K complex, phosphoinositide 3-kinase complex, class IB |
Definition: | A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks. |
Ontology: | GO: Cellular Component [GO:0005944] QuickGO AmiGO |