Term Name: | eukaryotic translation initiation factor 2B complex |
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Synonyms: | eIF-2B, eif2B |
Definition: | A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon. |
Ontology: | GO: Cellular Component [GO:0005851] QuickGO AmiGO |