Term Name: | mRNA cleavage and polyadenylation specificity factor complex |
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Synonyms: | CFII complex, cleavage and polyadenylylation specificity factor activity, CPF complex, CPSF complex |
Definition: | A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal. |
Ontology: | GO: Cellular Component [GO:0005847] QuickGO AmiGO |