Term Name: | heterotrimeric G-protein complex |
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Synonyms: | heterotrimeric G-protein GTPase activity, heterotrimeric G-protein GTPase, alpha-subunit, heterotrimeric G-protein GTPase, beta-subunit, heterotrimeric G-protein GTPase, gamma-subunit |
Definition: | Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G protein-coupled receptors to an effector protein. |
Ontology: | GO: Cellular Component [GO:0005834] QuickGO AmiGO |