Term Name: ribonuclease III activity
Synonyms: pre-mRNA 3'-end processing endonuclease, ribonuclease 3 activity, RNase III activity
Definition: Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
Ontology: GO: Molecular Function [GO:0004525]    QuickGO    AmiGO

Relationships
is a type of: double-stranded RNA-specific ribonuclease activity RNA endonuclease activity producing 5'-phosphomonoesters, hydrolytic mechanism