Term Name: | serine-type endopeptidase activity |
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Synonyms: | blood coagulation factor activity, serine elastase activity |
Definition: | Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine). |
Ontology: | GO: Molecular Function [GO:0004252] QuickGO AmiGO |