Term Name: serine-type endopeptidase activity
Synonyms: blood coagulation factor activity, serine elastase activity
Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
Ontology: GO: Molecular Function [GO:0004252]    QuickGO    AmiGO

Relationships
is a type of: endopeptidase activity serine-type peptidase activity
negatively regulated by: negative regulation of serine-type endopeptidase activity serine-type endopeptidase inhibitor activity
positively regulated by: positive regulation of serine-type endopeptidase activity
regulated by: regulation of serine-type endopeptidase activity