Term Name: | DNA-(apurinic or apyrimidinic site) endonuclease activity |
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Synonyms: | AP endonuclease class I activity, AP site-DNA 5'-phosphomonoester-lyase activity, apurinic/apyrimidinic endodeoxyribonuclease activity, deoxyribonuclease (apurinic or apyrimidinic) activity, DNA-(apurinic or apyrimidinic site) 5'-phosphomonoester-lyase activity, endonuclease VIII activity, UV endonuclease |
Definition: | Catalysis of the cleavage of the C-O-P bond in the AP site created when DNA glycosylase removes a damaged base, involved in the DNA base excision repair pathway (BER). |
Ontology: | GO: Molecular Function [GO:0003906] QuickGO AmiGO |