Term Name: | MAML1-RBP-Jkappa- ICN1 complex |
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Synonyms: | MAML1-CSL-ICN1, MAML1-CSL-Notch1 complex, MAML1-RBP-Jkappa-Notch1 complex |
Definition: | A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling. |
Ontology: | GO: Cellular Component [GO:0002193] QuickGO AmiGO |