Term Name: Lynch syndrome
Synonyms: Hereditary Defective Mismatch Repair syndrome, Hereditary non-polyposis colon cancer, Hereditary non-polyposis colon cancer syndrome, Hereditary non-polyposis colorectal cancer, Hereditary non-polyposis colorectal cancer syndrome, Hereditary nonpolyposis colon cancer, Hereditary nonpolyposis colon cancer syndrome, hereditary nonpolyposis colorectal cancer, Hereditary nonpolyposis colorectal cancer syndrome, hereditary nonpolyposis colorectal neoplasm, HNPCC
Definition: A syndrome that is characterized by an increased risk for colon cancer and cancers of the endometrium, ovary, stomach, small intestine, hepatobiliary tract, urinary tract, brain, and skin and has_material_basis_in mutation of mismatch repair genes that increases the risk of many types of cancers.
Ontology: Human Disease [DOID:3883]   ( DOID:3883 )

Relationships
is a type of: autosomal dominant disease syndrome
has subtype: hereditary nonpolyposis colorectal cancer type 2 hereditary nonpolyposis colorectal cancer type 4 hereditary nonpolyposis colorectal cancer type 5 hereditary nonpolyposis colorectal cancer type 6 hereditary nonpolyposis colorectal cancer type 7 hereditary nonpolyposis colorectal cancer type 8 Lynch syndrome 1 Muir-Torre syndrome