Term Name:	alpha 1-antitrypsin deficiency
Synonyms:	AAT deficiency
Definition:	A plasma protein metabolism disease that has_material_basis_in defective production of the protease inhibitor alpha 1-antitrypsin (A1AT), leading to decreased A1AT activity in the blood and lungs, and deposition of excessive abnormal A1AT protein in liver cells.
Ontology:	Human Disease [DOID:13372]   ( DOID:13372 )