Term Name:	core binding factor acute myeloid leukemia
Synonyms:
Definition:	An acute myeloid leukemia that is characterized by the presence of t(8;21)(q22;q22) or inv(16)(p13q22)/t(16;16)(p13;q22). These cytogenetic abnormalities result in disruption of the transcription factor CBF, which is a regulator of normal hematopoiesis.
Ontology:	Human Disease [DOID:0080796]   ( DOID:0080796 )