Term Name: | adult-onset leukoencephalopathy with axonal spheroids and pigmented glia |
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Synonyms: | hereditary diffuse leukoencephalopathy with spheroids |
Definition: | A leukodystrophy that is characterized by progressive dementia, apraxia, apathy, impaired balance, parkinsonism, spasticity and epilepsy and has_material_basis_in heterozygous mutation in the CSF1R gene on chromosome 5q32. |
Ontology: | Human Disease [DOID:0080523] ( DOID:0080523 ) |