Term Name:	early-onset progressive encephalopathy with brain atrophy and spasticity
Synonyms:	PEBAS
Definition:	An autosomal recessive intellectual developmental disorder characterized by microcephaly, global developmental delay, hearing loss, truncal hypotonia, appendicular spasticity, and dystonia and/or myoclonus that has_material_basis_in homozygous or compound heterozygous mutation in the TRAPPC12 gene on chromosome 2p25.
Ontology:	Human Disease [DOID:0070745]   ( DOID:0070745 )