Term Name:	adult-onset leukoencephalopathy without lacunae
Synonyms:	LUCAO
Definition:	A leukodystrophy characterized by a diffuse vascular leukoencephalopathy without lacunar infarct and a hippocampal type of memory defect with onset in the sixth to seventh decade that has_material_basis_in heterozygous mutation in the LAMB1 gene on chromosome 7q31.
Ontology:	Human Disease [DOID:0070722]   ( DOID:0070722 )