Term Name: | immunodeficiency 119 |
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Synonyms: | |
Definition: | A T cell, B cell, and NK cell deficiency that is characterized by the onset of recurrent upper and lower respiratory infections and warts in childhood and that has_material_basis_in homozygous mutation in the ICOSLG gene on chromosome 21q22. Affected individuals are susceptible to chronic DNA-based viral infections, including HPV and HSV. |
Ontology: | Human Disease [DOID:0061085] ( DOID:0061085 ) |