Term Name: pre-B-I cell
Synonyms: pre-BI cell, pro-B cell (Philadelphia nomenclature)
Definition: A pre-B-I cell is a precursor B cell that expresses CD34 and surrogate immunoglobulin light chain (VpreB , Lambda 5 (mouse)/14.1 (human)) on the cell surface, and TdT, Rag1,and Rag2 intracellularly. Cell type carries a D-JH DNA rearrangement, and lacks expression of immunglobulin heavy chain protein.
Ontology: Cell Ontology [CL:0000956]

Relationships
develops from: pro-B cell
is a type of: precursor B cell
has_part: DNA nucleotidylexotransferase V(D)J recombination-activating protein 1 V(D)J recombination-activating protein 2
has_plasma_membrane_part: CD34 molecule immunoglobulin iota chain immunoglobulin lambda-like polypeptide 1
inverse disjoint_from: pre-B-II cell
participates_in: immunoglobulin heavy chain V-D-J recombination