Term Name: naive thymus-derived CD8-positive, alpha-beta T cell
Synonyms: naive CD8+ T cell, naive thymus-dervied CD8-positive, alpha-beta T lymphocyte, naive thymus-dervied CD8-positive, alpha-beta T-cell, naive thymus-dervied CD8-positive, alpha-beta T-lymphocyte, T.8Nve.Sp
Definition: A CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low.
Ontology: Cell Ontology [CL:0000900]

Relationships
develops from: mature CD8 single-positive thymocyte
develops into: activated CD8-positive, alpha-beta T cell
is a type of: CD8-positive, alpha-beta T cell naive T cell
has_high_plasma_membrane_amount: L-selectin
has_low_plasma_membrane_amount: CD44 molecule
has_plasma_membrane_part: C-C chemokine receptor type 7 interleukin-7 receptor subunit alpha receptor-type tyrosine-protein phosphatase C isoform CD45RA
lacks_plasma_membrane_part: interleukin-2 receptor subunit alpha