Term Name: inflammatory macrophage
Synonyms: classically activated macrophage, M1 macrophage
Definition: An elicited macrophage that is recruited into the tissues in response to injury and infection as part of an inflammatory response, expresses high levels of pro-inflammatory cytokines, ROS and NO, and shows potent microbicidal activity.
Ontology: Cell Ontology [CL:0000863]

Relationships
is a type of: elicited macrophage
has subtype: kidney interstitial inflammatory macrophage
capable_of: defense response to bacterium interleukin-1 beta production interleukin-6 production obsolete nitric-oxide synthase biosynthetic process superoxide anion generation tumor necrosis factor production