Term Name: mast cell progenitor
Synonyms: CFU-Mast, CFU-MC, colony forming unit mast cell, MCP
Definition: A progenitor cell of the mast cell lineage. Markers for this cell are FceRIa-low, CD117-positive, CD9-positive, T1/ST2-positive, SCA1-negative, and lineage-negative.
Ontology: Cell Ontology [CL:0000831]

Relationships
develops from: basophil mast progenitor cell
develops into: mast cell
is a type of: myeloid cell myeloid lineage restricted progenitor cell
has subtype: Fc-epsilon RIalpha-low mast cell progenitor
capable_of: mast cell differentiation
has_high_plasma_membrane_amount: integrin beta-7
has_low_plasma_membrane_amount: high affinity immunoglobulin epsilon receptor subunit alpha mast/stem cell growth factor receptor
has_part: endothelial transcription factor GATA-2 erythroid transcription factor
has_plasma_membrane_part: CD9 molecule transmembrane emp24 domain-containing protein 1
lacks_part: CCAAT/enhancer-binding protein alpha
lacks_plasma_membrane_part: CD2 molecule CD3 epsilon CD4 molecule CD14 molecule CD19 molecule CD27 molecule integrin alpha-M lymphocyte antigen 6A-2/6E-1 lymphocyte antigen 6C2 lymphocyte antigen 6G lymphocyte antigen 76 membrane-spanning 4-domains subfamily A member 1 neural cell adhesion molecule 1 T-cell surface glycoprotein CD5 T-cell surface glycoprotein CD8 alpha chain