Term Name: | plasma cell |
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Synonyms: | effector B cell, effector B-cell, plasma B cell, plasma B-cell, plasmacyte, plasmocyte |
Definition: | A terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin. |
Ontology: | Cell Ontology [CL:0000786] |