Term Name: hematopoietic stem cell
Synonyms: blood forming stem cell, colony forming unit hematopoietic, hemopoietic stem cell, HSC
Definition: A stem cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system. Hematopoietic stem cells lack cell markers of effector cells (lin-negative). Lin-negative is defined by lacking one or more of the following cell surface markers: CD2, CD3 epsilon, CD4, CD5 ,CD8 alpha chain, CD11b, CD14, CD19, CD20, CD56, ly6G, ter119.
Ontology: Cell Ontology [CL:0000037]

Relationships
develops from: angioblastic mesenchymal cell
develops into: hematopoietic multipotent progenitor cell leukocyte plasmacytoid dendritic cell
is a type of: hematopoietic cell hematopoietic precursor cell somatic stem cell
has subtype: CD34-positive, CD38-negative hematopoietic stem cell cord blood hematopoietic stem cell gestational hematopoietic stem cell Kit and Sca1-positive hematopoietic stem cell peripheral blood stem cell placental hematopoietic stem cell
capable_of: hematopoietic progenitor cell differentiation somatic stem cell division
lacks_plasma_membrane_part: CD2 molecule CD3 epsilon CD4 molecule CD14 molecule CD19 molecule integrin alpha-M lymphocyte antigen 6G lymphocyte antigen 76 membrane-spanning 4-domains subfamily A member 1 neural cell adhesion molecule 1 T-cell surface glycoprotein CD5 T-cell surface glycoprotein CD8 alpha chain