Term Name: pyrimethamine
Synonyms: 2,4-Diamino-5-(4-chlorophenyl)-6-ethylpyrimidine, 2,4-Diamino-5-(p-chlorophenyl)-6-ethylpyrimidine, 2,4-Diamino-5-chlorophenyl-6-ethylpyrimidine, 5-(4'-Chlorophenyl)-2,4-diamino-6-ethylpyrimidine, 5-(4-Chlorophenyl)-6-ethyl-2,4-diaminopyrimidine, 5-(4-Chlorophenyl)-6-ethyl-2,4-pyrimidinediamine, 5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine, CD, Chloridine, Chloridyn, Diaminopyritamin, Ethylpyrimidine, pirimetamina, Primethamine, pyrimethamine, pyrimethaminum
Definition: An aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a p-chlorophenyl group and at position 6 by an ethyl group. It is a folic acid antagonist used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Ontology: Chebi [CHEBI:8673]

Relationships
is a type of: aminopyrimidine monochlorobenzenes
has_role: antimalarial antiprotozoal drug EC 1.5.1.3 (dihydrofolate reductase) inhibitor