Term Name: | cytarabine |
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Synonyms: | 1-beta-D-Arabinofuranosylcytosine, 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone, 4-amino-1-beta-D-arabinofuranosylpyrimidin-2(1H)-one, ara-C, arabinocytosine, Arabinoside C, citarabina, cytarabine, cytarabinum, Cytosine arabinoside, Cytosine-1-beta-D-arabinofuranoside, cytosine-beta-D-arabinofuranoside |
Definition: | A pyrimidine nucleoside in which cytosine is attached to D-arabinofuranose via a beta-N(1)-glycosidic bond. Used mainly in the treatment of leukaemia, especially acute non-lymphoblastic leukaemia, cytarabine is an antimetabolite antineoplastic agent that inhibits the synthesis of DNA. It also has antiviral and immunosuppressant properties. |
Ontology: | ChEBI [CHEBI:28680] ( EBI ) |