Term Name: | AR-42 |
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Synonyms: | (S)-HDAC 42, (S)-HDAC-42, AR 42, AR42, HDAC-42, N-hydroxy-4-[[(2S)-3-methyl-2-phenylbutanoyl]amino]benzamide, N-hydroxy-4-{[(2S)-3-methyl-2-phenylbutanoyl]amino}benzamide, OSU-HDAC42, REC 2282, REC-2282, REC2282 |
Definition: | A secondary carboxamide resulting from the formal condensation of the carboxy group of (2S)-3-methyl-2-phenylbutanoic acid with the amino group of 4-amino-N-hydroxybenzamide. It is a pan-HDAC inhibitor that was in clinical development for the treatment of hematological malignancies and solid tumours. |
Ontology: | ChEBI [CHEBI:188197] ( EBI ) |