Term Name: tris
Synonyms: 1,1,1-tris(hydroxymethyl)methanamine, 2-Amino-2-(hydroxymethyl)-1,3-propanediol, 2-amino-2-(hydroxymethyl)propane-1,3-diol, aminotris(hydroxymethyl)methane, THAM, Tris, Tris amino, Tris base, Tris buffer, tris(hydroxymethyl)aminomethane, Tris-base, Trizma, Trometamol, Tromethamine
Definition: A primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 degreeC; pKa = 7.82 at 37 degreeC.
Ontology: ChEBI [CHEBI:9754]  ( EBI )

Relationships
is a type of: primary amino compound triol
has_role: buffer
inverse has_functional_parent: bis-tris bis-tris propane N-tris(hydroxymethyl)methylglycine TES
inverse is_conjugate_acid_of: Htris
is_conjugate_base_of: Htris