Term Name: lumacaftor
Synonyms: 3-(6-{[1-(2,2-difluoro-2H-1,3-benzodioxol-5-yl)cyclopropane-1-carbonyl]amino}-3-methylpyridin-2-yl)benzoic acid, lumacaftor, VRT 826809, VRT-826809, VX 809, VX-809
Definition: An aromatic amide obtained by formal condensation of the carboxy group of 1-(2,2-difluoro-1,3-benzodioxol-5-yl)cyclopropane-1-carboxylic acid with the aromatic amino group of 3-(6-amino-3-methylpyridin-2-yl)benzoic acid. Used for the treatment of cystic fibrosis.
Ontology: ChEBI [CHEBI:90951]  ( EBI )

Relationships
is a type of: aromatic amide benzodioxoles benzoic acids cyclopropanes organofluorine compound pyridines
has_role: CFTR potentiator orphan drug
inverse has_part: Orkambi