Term Name:	tenofovir alafenamide
Synonyms:	GS 7340, GS-7340, propan-2-yl N-[(S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl]-L-alaninate, TAF, tenofovir alafenamide
Definition:	An L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)(phenoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection.
Ontology:	ChEBI [CHEBI:90926] ( EBI )

Relationships

is a type of:	6-aminopurines ether isopropyl ester L-alanine derivative phosphoramidate ester
has_functional_parent:	adenine
has_role:	antiviral drug HIV-1 reverse transcriptase inhibitor prodrug
inverse is_conjugate_acid_of:	tenofovir alafenamide(1+)
is_conjugate_base_of:	tenofovir alafenamide(1+)