Term Name: tipiracil
Synonyms: 5-chloro-6-[(2-iminopyrrolidin-1-yl)methyl]pyrimidine-2,4(1H,3H)-dione, tipiracil
Definition: A member of the class of pyrimidones that is uracil substituted by chloro and (2-iminopyrrolidin-1-yl)methyl groups at positions 5 and 6 respectively. Used (as the hydrochloride salt) in combination with trifluridine, a nucleoside metabolic inhibitor, for treatment of advanced/relapsed unresectable colorectal cancer.
Ontology: ChEBI [CHEBI:90879]  ( EBI )

Relationships
is a type of: carboxamidine organochlorine compound pyrimidone pyrrolidines
has_functional_parent: uracil
has_role: antineoplastic agent EC 2.4.2.4 (thymidine phosphorylase) inhibitor
inverse is_conjugate_acid_of: tipiracil(1+)
is_conjugate_base_of: tipiracil(1+)