Term Name: sonidegib
Synonyms: Erismodegib, LDE 225, LDE-225, LDE225, N-[6-(cis-2,6-dimethylmorpholin-4-yl)pyridin-3-yl]-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide, NVP-LDE 225, NVP-LDE225, rel-N-{6-[(2R,6S)-2,6-dimethylmorpholin-4-yl]pyridin-3-yl}-2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxamide, sonidegib
Definition: A member of the classo of biphenyls that is the amide obtained by formal condensation of the carboxy group of 2-methyl-4'-(trifluoromethoxy)[1,1'-biphenyl]-3-carboxylic acid with the amino group of 6-(2,6-dimethylmorpholin-4-yl)pyridin-3-amine. Used (as its phosphate salt) for treatment of locally advanced basal cell carcinoma.
Ontology: ChEBI [CHEBI:90863]  ( EBI )

Relationships
is a type of: aminopyridine aromatic ether benzamides biphenyls morpholines organofluorine compound tertiary amino compound
has_role: antineoplastic agent Hedgehog signaling pathway inhibitor SMO receptor antagonist
inverse has_part: sonidegib phosphate