Term Name: RU 58668
Synonyms: (11beta,17beta)-11-[4-({5-[(4,4,5,5,5-pentafluoropentyl)sulfonyl]pentyl}oxy)phenyl]estra-1,3,5(10)-triene-3,17-diol, 11beta-[4-({5-[(4,4,5,5,5-pentafluoropentyl)sulfonyl]pentyl}oxy)phenyl]-17beta-estradiol, 11beta-[4-({5-[(4,4,5,5,5-pentafluoropentyl)sulfonyl]pentyl}oxy)phenyl]estra-1,3,5(10)-triene-3,17beta-diol, RU 58 668, RU 58,668, RU-58668, RU58668
Definition: A 17beta-hydroxy steroid that is 17beta-estradiol in the the hydrogen at the 11beta position has been replaced by a p-({5-[(4,4,5,5,5-pentafluoropentyl)sulfonyl]pentyl}oxy)phenyl group. RU 58668 is a pure anti-estrogen that downregulates estrogen receptor expression (IC50 = 0.04 nM).
Ontology: ChEBI [CHEBI:90223]  ( EBI )

Relationships
is a type of: 3-hydroxy steroid 17beta-hydroxy steroid aromatic ether organofluorine compound sulfone
has_role: anti-estrogen antineoplastic agent estrogen receptor antagonist