Term Name:	rac-selisistat
Synonyms:	EX-527, rac-6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide, rac-EX-527, salisistat, selisistat, selisistatum
Definition:	A racemate comprising equimolar amounts of (R)- and (S)-selisistat. It is a potent sirtuin 1 (SIRT1) inhibitor (IC50 38 nM) and is 200-500-fold more selective for SIRT1 than for SIRT2 or SIRT3. The active isomer (EX-243) gives similar results and potency; the enantiomer (EX-242) is inactive.
Ontology:	ChEBI [CHEBI:90196]  ( EBI )