Term Name: rofecoxib
Synonyms: 3-phenyl-4-[4-(methylsulfonyl)phenyl]-2(5H)-furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenyl-2(5H)-furanone, 4-[4-(methylsulfonyl)phenyl]-3-phenylfuran-2(5H)-one, Ceoxx, Rofecoxib, rofecoxibum, Vioxx
Definition: A butenolide that is furan-2(5H)-one substituted by a phenyl group at position 3 and by a p-(methylsulfonyl)phenyl group at position 4. A selective cyclooxygenase 2 inhibitor, it was used from 1999 to 2004 for the treatment of ostoarthritis, but was withdrawn following concerns about an associated increased risk of heart attack and stroke.
Ontology: ChEBI [CHEBI:8887]  ( EBI )

Relationships
is a type of: butenolide sulfone
has_role: analgesic cyclooxygenase 2 inhibitor non-steroidal anti-inflammatory drug