Term Name: LGK974
Synonyms: 2-(2',3-dimethyl-2,4'-bipyridin-5-yl)-N-[5-(pyrazin-2-yl)pyridin-2-yl]acetamide
Definition: A carboxamide, the structure of which is that of acetamide substituted on carbon by a 2',3-dimethyl-2,4'-bipyridin-5-yl group and on nitrogen by a 5-(pyrazin-2-yl)pyridin-2-yl group. It is a highly potent, selective and orally bioavailable Porcupine inhibitor (a Wnt signalling inhibitor).
Ontology: ChEBI [CHEBI:78030]  ( EBI )

Relationships
is a type of: bipyridines pyrazines pyridines secondary carboxamide
has_functional_parent: acetamide
has_role: Wnt signalling inhibitor