Term Name: rac-nortilidine
Synonyms: (+-)-ethyl trans-2-methylamino-1-phenyl-3-cyclohexene-trans-1-carboxylate, nortilidine, rac-ethyl (1R,2S)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate, rac-ethyl (1S,2R)-2-(methylamino)-1-phenylcyclohex-3-ene-1-carboxylate
Definition: A racemate comprising (1R,2S)- and (1S,2R)-nortilidine. The synthetic narcotic analgesic tilidine is a prodrug for nortilidine, being metabolised to it in the liver. Virtually all of the opioid analgesic effects of racemic nortilidine, which are comparable to those of morphine, are due to the (1S,2R) enantiomer.
Ontology: ChEBI [CHEBI:77829]  ( EBI )

Relationships
is a type of: racemate
has_part: (1R,2S)-nortilidine (1S,2R)-nortilidine
has_role: drug metabolite opioid analgesic