Term Name: (S)-ketorolac
Synonyms: (-)-ketorolac, (1S)-5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, (S)-(-)-ketorolac
Definition: A 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid that has S configuration. While (S)-ketorolac is a COX1 and COX2 inhibitor, both enantiomers exhibit analgesic effects. Racemic ketorolac, known simply as ketorolac, is used (mainly as the tromethamine salt) as a potent analgesic for the short-term management of post-operative pain, and in eye drops to relieve the ocular itching associated with seasonal allergic conjunctivitis.
Ontology: ChEBI [CHEBI:76228]  ( EBI )

Relationships
is a type of: 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
has_role: analgesic cyclooxygenase 1 inhibitor cyclooxygenase 2 inhibitor non-steroidal anti-inflammatory drug
inverse has_part: ketorolac
inverse is_enantiomer_of: (R)-ketorolac
is_enantiomer_of: (R)-ketorolac