Term Name: indoprofen
Synonyms: 1-Oxo-2-(p-((alpha-methyl)carboxymethyl)phenyl)isoindoline, 2-(4-(1-Carboxyethyl)phenyl)-1-isoindolinone, 2-[4-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)phenyl]propanoic acid, alpha-(4-(1-Oxo-2-isoindolinyl)phenyl)propionic acid, indoprofen, indoprofene, indoprofeno, indoprofenum, K 4277
Definition: A monocarboxylic acid that is propionic acid in which one of the hydrogens at position 2 is substituted by a 4-(1-oxo-1,3-dihydroisoindol-2-yl)phenyl group. Initially used as an anti-inflammatory and analgesic, it was withdrawn from the market due to causing severe gastrointestinal bleeding. It has been subsequently found to increase production of the survival motor neuron protein.
Ontology: ChEBI [CHEBI:76162]  ( EBI )

Relationships
is a type of: gamma-lactam isoindoles monocarboxylic acid
has_functional_parent: propionic acid
has_role: EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor non-narcotic analgesic non-steroidal anti-inflammatory drug