Term Name: | deglymidodrine |
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Synonyms: | (+-)-2-amino-1-(2,5-dimethoxyphenyl)ethanol, (+/-)-2-amino-1-(2,5-dimethoxyphenyl)ethanol, 1-(2',5'-dimethoxyphenyl)aminoethanol, alpha-(aminomethyl)-2,5-dimethoxybenzenemethanol, de-glymidodrine, desglymidodrine, rac-2-amino-1-(2,5-dimethoxyphenyl)ethanol, ST-1059 |
Definition: | An aromatic ether that is 1,4-dimethoxybenzene which is substituted at position 2 by a 2-amino-1-hydroxyethyl group. The immediate and active metabolite of midrodine, it is a direct-acting sympathomimetic with selective alpha-adrenergic agonist activity. Midrodine is used (generally as its hydrochloride salt) as a prodrug for deglymidodrine, which acts as a peripheral vasoconstrictor in the treatment of certain hypotensive states. |
Ontology: | ChEBI [CHEBI:73248] ( EBI ) |