Term Name: nisin
Synonyms: E234, EINECS 215-807-5, N-{[(1S,4S,7S,8S,11R,14S,17R,20S)-7-{[N(2)-({(3R,9S,12S,15S,21S,22S)-21-[(N(2)-{[(6R,9S,10S,15aS)-10-({[(3R,6S,12S,15S)-12-[(2S)-butan-2-yl]-6-isobutyl-15-{[(2Z)-2-(L-isoleucylamino)but-2-enoyl]amino}-9-methylene-5,8,11,14-tetraoxo-1-thia-4,7,10,13-tetraa, NSC 112903, NSC-112903
Definition: A type-A lantibiotic containing 34 amino acid residues (including lanthionine (Lan), methyllanthionine (MeLan), didehydroalanine (Dha) and didehydroaminobutyric acid (Dhb)) and five thioether bridges. It is obtained by fermentation of the bacterium Lactococcus lactis and shows particular activity against Clostridium botulinum. It is used in the production of various processed foods to suppress Gram-positive spoilage and pathogenic bacteria and so extend shelf life.
Ontology: ChEBI [CHEBI:71629]  ( EBI )

Relationships
is a type of: macrocycle type A lantibiotic
has_role: antibacterial agent antimicrobial food preservative metabolite