Term Name: | procarbazine |
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Synonyms: | 1-Methyl-2-(p-(isopropylcarbamoyl)benzyl)hydrazine, 2-(p-Isopropylcarbamoylbenzyl)-1-methylhydrazine, 4-((2-Methylhydrazino)methyl)-N-isopropylbenzamide, N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide, N-(1-methylethyl)-4-[(2-methylhydrazino)methyl]benzamide, N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine, N-isopropyl-4-[(2-methylhydrazino)methyl]benzamide, N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide, N-Isopropyl-p-(2-methylhydrazinomethyl)-benzamide, p-(2-Methylhydrazinomethyl)-N-isopropylbenzamide, Procarbazin, procarbazina, procarbazine, procarbazinum |
Definition: | A benzamide obtained by formal condensation of the carboxy group of 4-[(2-methylhydrazino)methyl]benzoic acid with the amino group of isopropylamine. An antineoplastic chemotherapy drug used for treatment of Hodgkin's lymphoma. Metabolism yields azo-procarbazine and hydrogen peroxide, which results in the breaking of DNA strands. |
Ontology: | ChEBI [CHEBI:71417] ( EBI ) |