Term Name: latrunculin A
Synonyms: (+)-latrunculin A, (4R)-4-[(1R,4Z,8E,10Z,12S,15R,17R)-17-hydroxy-5,12-dimethyl-3-oxo-2,16-dioxabicyclo[13.3.1]nonadeca-4,8,10-trien-17-yl]-1,3-thiazolidin-2-one, LAT-A, LatA, LATRUNCULIN A, NSC 613011
Definition: A bicyclic macrolide natural product consisting of a 16-membered bicyclic lactone attached to the rare 2-thiazolidinone moiety. It is obtained from the Red Sea sponge Latrunculia magnifica and from the Fiji Islands sponge Cacospongia mycofijiensis. Latrunculin A inhibits actin polymerisation, microfilament organsation and microfilament-mediated processes.
Ontology: ChEBI [CHEBI:69136]  ( EBI )

Relationships
is a type of: cyclic hemiketal macrolide oxabicycloalkane thiazolidinone
has_role: actin polymerisation inhibitor metabolite toxin